Orencia 250 mg



Bristol-Myers Squibb

Orencia®  250 mg 1 vial (Abadacept)

Orencia® (abatacept) is a biologic medicine that reduces the pain and swelling of moderate to severe Rheumatoid Arthritis (RA) and can help stop further joint damage.

It reduces signs and symptoms in adults with moderate to severe RA, including those who have not been helped enough by other medicines for RA. Orencia® may prevent further damage to your bones and joints and may help your ability to perform daily activities. In adults, Orencia® may be used alone or with other RA treatments other than tumor necrosis factor (TNF) antagonists.

Orencia® for Injection is a lyophilized powder for intravenous infusion. Orencia® for Injection is supplied as a sterile, white, preservative-free, lyophilized powder for reconstitution and dilution prior to intravenous administration. Following reconstitution of the lyophilized powder with 10 mL of Sterile Water for Injection, USP, the solution of Orencia® is clear, colorless to pale yellow, with a pH range of 7.2 to 7.8. Each single-use vial of Orencia® for Injection provides 250 mg abatacept, maltose (500 mg), monobasic sodium phosphate (17.2 mg), and sodium chloride (14.6 mg) for administration.

Orencia® Injection is a sterile, preservative-free, clear to slightly opalescent, colorless to paleyellow solution with a pH range of 6.8 to 7.4 for subcutaneous administration. Orencia® Injection is supplied as a single-dose prefilled syringe or as a single-dose ClickJect autoinjector.

Orencia® can cause such side effects as serious infections, allergic reactions, hepatitis B infection in carriers of the virus, interactions with vaccines, respiratory problems with chronic obstructive pulmonary disease (COPD), and cancer. Side effects of Orencia® which are considered common include: headache, upper respiratory tract infection, sore throat, and nausea. Other side effects in children and adolescents include diarrhea, cough, fever, and abdominal pain.

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